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Masaru Taniguchi Selected Research

KRN 7000 (KRN7000)

1/2014Synthesis of RCAI-172 (C6 epimer of RCAI-147) and its biological activity.
4/2013Synthesis and biological activity of hydroxylated analogues of KRN7000 (α-galactosylceramide).
3/2011Induction of NKT cell-specific immune responses in cancer tissues after NKT cell-targeted adoptive immunotherapy.
8/2008Prophylaxis of lipopolysaccharide-induced shock by alpha-galactosylceramide.

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Masaru Taniguchi Research Topics

Disease

28Neoplasms (Cancer)
01/2017 - 03/2002
10Inflammation (Inflammations)
09/2013 - 08/2002
8Infections
01/2016 - 01/2002
5Hypersensitivity (Allergy)
01/2016 - 10/2005
5Lung Neoplasms (Lung Cancer)
10/2012 - 03/2005
5Asthma (Bronchial Asthma)
01/2012 - 05/2003
4Neoplasm Metastasis (Metastasis)
03/2015 - 09/2003
4Seasonal Allergic Rhinitis (Hay Fever)
01/2015 - 01/2010
3Uveitis
01/2021 - 11/2005
3Type 1 Diabetes Mellitus (Autoimmune Diabetes)
01/2018 - 10/2005
3Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
02/2009 - 03/2005
3Experimental Melanoma
01/2008 - 03/2007
2Hyperglycemia
01/2018 - 04/2007
2Communicable Diseases (Infectious Diseases)
01/2016 - 09/2004
2Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
01/2014 - 04/2013
2Autoimmune Diseases (Autoimmune Disease)
04/2013 - 01/2003
2Rhinitis
01/2012 - 07/2008
2Squamous Cell Carcinoma of Head and Neck
03/2011 - 06/2009
2Hepatitis
01/2010 - 10/2004
2Graft vs Host Disease (Graft-Versus-Host Disease)
09/2008 - 07/2005
2Melanoma (Melanoma, Malignant)
01/2008 - 10/2007
2Respiratory Hypersensitivity
10/2005 - 08/2002
2Malaria
02/2005 - 03/2002
2Colitis
01/2005 - 03/2003
2Granuloma
02/2004 - 08/2003
1Poisoning
01/2021
1Candidiasis (Moniliasis)
01/2016
1B-Cell Lymphoma (Lymphoma, B Cell)
01/2016
1Human Influenza (Influenza)
01/2014
1Virus Diseases (Viral Diseases)
01/2014
1Myocardial Ischemia (Ischemic Heart Diseases)
09/2013
1Reperfusion Injury
09/2013
1Candidemia
01/2012
1Food Hypersensitivity (Food Allergy)
01/2012
1Persistent Infection
05/2011
1Pathologic Processes
12/2009
1Carcinoma (Carcinomatosis)
06/2009
1Demyelinating Diseases (Demyelinating Disease)
01/2009
1Septic Shock (Toxic Shock Syndrome)
08/2008
1Shock
08/2008
1Head and Neck Neoplasms (Head and Neck Cancer)
03/2008
1Corneal Neovascularization
01/2008
1Pneumococcal Infections
03/2007
1Proteinuria
02/2007

Drug/Important Bio-Agent (IBA)

20alpha-galactosylceramideIBA
06/2009 - 03/2002
14AntigensIBA
12/2016 - 03/2002
14CytokinesIBA
01/2014 - 05/2002
9LigandsIBA
01/2017 - 05/2004
8GlycolipidsIBA
03/2014 - 03/2002
7Interleukin-4 (Interleukin 4)IBA
04/2013 - 01/2002
5Galactosylceramides (Galactocerebrosides)IBA
01/2016 - 11/2010
5Immunoglobulin E (IgE)IBA
01/2016 - 10/2005
5VaccinesIBA
01/2016 - 03/2002
5AllergensIBA
01/2015 - 05/2003
5Interferon-gamma (Interferon, gamma)IBA
03/2014 - 01/2002
4AntibodiesIBA
03/2015 - 08/2003
4KRN 7000 (KRN7000)IBA
01/2014 - 08/2008
3Interleukin-18 (Interleukin 18)IBA
01/2016 - 02/2003
3Immunoglobulin G (IgG)IBA
01/2016 - 03/2002
3Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
08/2008 - 08/2003
2Peptides (Polypeptides)IBA
12/2016 - 10/2007
2Interleukin-10 (Interleukin 10)IBA
01/2016 - 05/2011
2Proteins (Proteins, Gene)FDA Link
01/2015 - 02/2008
2Antifungal AgentsIBA
03/2014 - 01/2012
2Messenger RNA (mRNA)IBA
12/2013 - 08/2003
2Biomarkers (Surrogate Marker)IBA
04/2011 - 01/2010
2InterferonsIBA
11/2010 - 02/2008
2Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA
02/2009 - 07/2003
2LipopolysaccharidesIBA
08/2008 - 11/2006
2Interleukin-12 (IL 12)IBA
02/2008 - 01/2002
2Interleukin-13IBA
01/2007 - 10/2005
2OvalbuminIBA
11/2005 - 10/2005
2Interleukin-5 (Interleukin 5)IBA
10/2005 - 08/2002
2AutoantigensIBA
06/2005 - 09/2003
2EpitopesIBA
10/2004 - 09/2003
1Protoveratrines (Protoveratrine A)IBA
01/2021
1interstitial retinol-binding proteinIBA
12/2016
1Freund's AdjuvantIBA
12/2016
1Transcription Factors (Transcription Factor)IBA
01/2016
1Antineoplastic Agents (Antineoplastics)IBA
01/2014
1SphingosineIBA
04/2013
1Indicators and Reagents (Reagents)IBA
04/2010
1SugarsIBA
04/2010
1Calcium-Independent Phospholipases A2IBA
12/2009
1CalciumIBA
12/2009
1Phospholipases (Phospholipase)IBA
12/2009
1Interleukin-2 (IL2)IBA
02/2009
1Fibroblast Growth Factor 7FDA Link
09/2008
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2008
1Chemokine CXCL16IBA
12/2007
1Streptozocin (Streptozotocin)FDA Link
04/2007
1Cardiolipins (Cardiolipin)IBA
02/2007

Therapy/Procedure

13Therapeutics
01/2021 - 05/2003
9Immunotherapy
01/2017 - 11/2002
5Transplantation
01/2018 - 07/2002
4Injections
06/2009 - 10/2004
2Islets of Langerhans Transplantation
01/2018 - 03/2010
2Intravenous Injections
10/2012 - 02/2008
2Intra-Arterial Infusions
03/2011 - 06/2009
1Cautery
01/2008